One of three types of [ ionotropic receptors|ionotropic ] [ glutamate ] receptor, along with [ NMDA receptor ]s and kainate receptors. It is…
A major inhibitory [ neurotransmitter ] in the brain. Related to the action of [ ethanol ] and other depressants and anesthetics. TODO…
(from [ Principles of Neural Design ]): a G protein skates along the inside of a cell membrane, bumping into the undersides of…
GHB is gamma-hydroxybutyrate (or gamma-hydroxybutyric acid): It is produced endogenously in the body, and agonizes a couple of receptor…
References: Dayan, Hinton, Neal, Zemel (1994) https://www.cs.toronto.edu/~hinton/absps/helmholtz.pdf This paper is one of the first to…
One of three types of [ ionotropic receptors|ionotropic ] [ glutamate ] receptor, along with [ AMPA receptor ]s and kainate receptors. It is…
Chapter 2: why an animal needs a brain. Brains allow for control and adaptation within a single lifetime. They make more sense for bigger…
One of the best ideas in machine learning. (I even thought so in 2011!) There are two common mechanisms: 'soft' and 'hard'. In both cases…
Antidepressent that acts as a [ norepinephrine ]-[ dopamine ] reuptake inhibitor. In the class of substituted [ phenethylamine ]s and (more…
Endocannabinoids are retrograde [ neurotransmitter ]s, meaning that they pass 'backwards' (from dendrite to axon) through the synaptic cleft…
A set of connected brain regions that are active when you're 'at rest', not focused on the external world. This includes mental states such…
Chemically, dopamine is a benzene ring (aka phenyl group), with two hydroxyl (OH) groups at adjacent sites, and a two-carbon (ethyl) chain…
Chemically, glutamate is the [ acid-base chemistry|conjugate base ] of glutamic acid (an [ amino acid ]). It is an [ anion ]; its sodium…
Effects in the brain Ketamine is an antagonist of [ NMDA receptor ]s, and activates [ AMPA receptor ]s. References: Ketamine – Lorien…
Described, among other places, in Unlocking the Emotional Brain . Insofar as much of Buddhism is about dissolving [ samskara ]s…
Parts of a neuron: dendrites: these branch out to receive connections from other cells axons: these branch out to send signals to other…
Obligatory disclaimer: there will never be a drug to turn you into Einstein. Most of effective high-level thinking lies in 'software…
There are 14 kinds of serotonin receptors; most (but not all) are [ G protein ]-coupled. The central nervous system has almost all of them…
References: https://redwood.berkeley.edu/wp-content/uploads/2020/08/KanervaP_SDMrelated_models1993.pdf A sparse distributed memory consists…